How to Launch a Successful, Cost-Effective Neurodevelopmental Study

2019-06-13T14:33:38+00:00By |

Many neurological conditions, including cerebral palsy, ADHD, epilepsy and autism, manifest either at birth or during childhood. Developing treatments for these diseases is challenging enough. Add to that the clinical, ethical and regulatory concerns that come with investigating drugs and devices for the pediatric population, and it's no surprise this vulnerable segment [...]

Rare Disease Spotlight: C3 Glomerulopathy

2019-06-11T10:16:22+00:00By |

C3 glomerulopathy (C3G), a rare kidney disease, affects only two or three people out of every one million. That's only a couple people out of the entire population of San Jose, California or Austin, Texas. Although C3G only affects a select few, without treatment it can lead to severe kidney damage and [...]

Modern Challenges in Movement Disorders Clinical Trials

2019-06-06T16:55:37+00:00By |

Movement disorders such as Parkinson’s disease, ataxias, tremor, dystonia, tics, Tourette’s, and dozens of rare diseases, affect nearly 40 million Americans. They're usually chronic, often progressive, and rarely curable. As our population ages, developing effective treatments for movement disorders has become critically important for the health of our population as well as [...]

Patient Recruitment Challenges in Dermatology Clinical Trials

2019-06-06T16:56:22+00:00By |

Eczema affects more people in the United States than diabetes (10.1 vs. 9.4 million)1,2. More than 8 million Americans have psoriasis.3 Considering how common some skin conditions are, one would assume sponsors would have no trouble finding clinical trial participants. Not necessarily. Although many dermatological conditions affect millions of people, dermatology clinical [...]

Are Cannabinoid-Derived Drugs the Future of Medicine?

2019-05-14T10:40:43+00:00By |

Less than a year ago, FDA approved the first cannabinoid-derived drug, Epidiolex. It's a pivotal development for a few reasons: It's the first FDA-approved drug to contain cannabidiol (CBD), a chemical component of the Cannabis sativa plant, aka, marijuana.It treats Dravet syndrome and Lennox-Gastaut syndrome, two rare and severe forms of epilepsy [...]

Is Gut Microbiome Behind Our Next Breakthrough Therapy?

2019-06-06T17:00:11+00:00By |

"Microbiome" has become a consumer product buzzword, found in advertisements for soap and dozens of foods that contain "friendly bacteria." Meanwhile, the scientific community is discovering new connections between the microbiome and our physical and mental health. Manipulating the microbiome may, in time, lead to cures and more targeted treatments. The microbiome–gut–brain [...]

Cellular Therapy in Neurological Diseases: The Latest Advances and Challenges

2019-04-17T14:54:21+00:00By |

Neurological disorders and diseases affect all ages and ethnicities, and most result in long-term disability and irreversible conditions. A paper published in the Annals of Neurology reports the nine most common neurological diseases cost the United States nearly $800 billion a year. As our population ages and the prevalence of conditions such as Alzheimer's [...]

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